If you have no interpreters declared and one or more FastCGI programs (which paths are incuded inside one of the "Script Paths"), you'll experience a crash when the FastCGI launch is being requested.
That's a (stupid) bug with 2.4.0.3 only. We'll provide a fix by the weekend.
Meanwhile, either delcare an interpreter in your configuration (even a fake one) or wait for 2.4.0.4.